Facilities/Resources
 The
Genome Science Research Building 2 (GSRB2; pictured below) is home to to 4 core faculty (Bilbo, Meck, Williams &
Yin). The third floor (21,444 gross sq. ft.) is a state of
the art, 4-year old facility, for the study of brain and behavior
using small animals as subjects. Experimental rooms for behavioral analysis
are equipped with radial-arm and water and Barnes' mazes, activity
boxes, startle, and operant conditioning chambers for study of
cognitive processes in small rodents. All behavioral test areas are
soundproofed and are across the hall from animal housing. There are
video-tracking systems in several of the procedure rooms that allow
continuous recording in both light and dark phases of the day;
computer programs allow for automated collection and analysis of maze
and operant data. Home cage wheel running and general activity can be
monitored remotely. Wet labs for analysis of RNA, DNA, and immediate
early genes, as well as fully equipped histology suite, and several
electrophysiology rigs are also available.
Laboratory space: includes
desktop computers for each graduate student and offices for
postdoctoral fellows. Communal
labs available to faculty and Trainees include:
Surgical suite:
designed for small animal surgeries and perfusions. It includes a
biosafety hood, chemical hood with sink, 2 surgical stations for use
with injectable or gas anesthesia, and an anti-room with
refrigerator, ice machine, sink and counters for preparing animals
for surgery.
Histology: houses standard hooded sink and a
vented work station, as well as a radioisotope hood for assays, fully
equipped with standard stirrers, shakers, balances, vibratome,
microtome, cryostat.
Image analysis: Features 2 Nikon
microscopes with video image analysis capability as well as
stereology software (Stereologer, Microbrightfield, Inc.) attached to
a motorized stage and high resolution video camera. An Olympus
epifluorescence microscope is also available.
Electrophysiology suites: equipped with a Plexon recording system for
sleep analysis, single or ensemble recording studies,
Molecular
biology suite: used for analysis of RNA, DNA (both PCR and fluorescence in situ).
Thirteen
animal housing rooms provide ample caging for mice, rats, pigeons and
fish for all researchers. All caging (Allentown) is individually
ventilated and both bottle water and automatic watering systems are
available. A cage wash facility, storage for food and bedding, and
general equipment are shared by all researchers on the floor.
 The
main offices of the Department of Psychology and Neuroscience are
located on West campus in one of the original Duke University
buildings (creatively named the Sociology-Psychology Building)
constructed in the early 1930's. Although the neogothic stone
exterior looks like something from a movie set, the building contains
the chair and staff offices, as well as the laboratories for many PBS
faculty. The department also has facilities and resources for
cognitive neuroscience research in the Center for Cognitive
Neuroscience (housed in the Levine Science Research Center-LSRC) and
in the Brain Imaging and Analysis Center-BIAC (housed in the Medical
Center). Facilities and laboratories for our Systems and Integrative
Neuroscience faculty are located in the Genome Sciences Research
Building II (GSRBII) located on Research Drive.
The
Sociology-Psychology building houses the laboratory of Dr. Schmajuk.
The research suites of individual investigators include subject
testing areas as well as desk and meeting space for lab personnel.
 The
Center for Cognitive Neuroscience houses the office and laboratory of Dr. Groh along with other researchers in the Center (see photo).
Dr. Groh's behavioral and electrophysiology testing suite for monkeys is located in
the University Vivarium which is a building connected to GSRB-II.
Faculty at the CCN do their imaging work in the associated Brain
Imaging and Analysis Center.
Other
Research Facilities relevant to SINS Faculty and Students
Duke Institute for Brain Sciences (DIBS) - A new Institute at Duke that seeks to seed innovation and collaboration in the Brain Sciences that transcends
the boundaries of traditional disciplines and integrates brain sciences
with the biomedical sciences, social sciences, life sciences, physical
sciences, humanities, law, business, mathematics, computer sciences,
and engineering.
Department
of Neurobiology is located entirely within the Joseph and Kathleen
Bryan Research Building, occupying approximately 32,000 sq. ft. of
laboratory, office and administrative space. It is a one-minute walk
from CCN, BIAC, GSRBII. The Department has fully equipped
laboratories for work ranging from visual psychophysics to single
neuron recording in awake, behaving monkeys, to molecular analysis of
synaptic function.
Department
of Psychiatry and Behavioral Sciences is actively involved in three
major areas of research: 1) the understanding of the biological,
social and behavioral mechanisms of psychiatric disorders 2) the role
of behavior and the central nervous system in somatic disease, 3)
clinical trials aimed at the design and implementation of new Major
topics currently being addressed by Departmental investigators
include mood disorders, schizophrenia, anxiety disorders,
attention-deficit disorders, memory disorders, cardiovascular
disease, diabetes mellitus and obesity.
Institute
of Genome Sciences and Policy is Duke University's response to the
array of advances in the Genome Sciences over the last decade. It
offers, via it's many centers, a comprehensive approach to the study
of life. The Institute, via its training programs, talk series, and
integrative outreach brings together scientists, engineers,
physicians, lawyers, policy makers, business leaders, economists,
ethicists, and humanists to explore the genome.
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